Achieve the refined, luminous glass skin look inspired by Asian beauty ideals. Once Korea’s most coveted skincare innovation, the Rejuran Skin Booster is now available at the Aesthetic Medicine Clinic by Dr. Nasser Madi in Geneva.
Designed to restore skin quality from within, this premium biostimulation treatment delivers “The Invisible Touch”: sophisticated, deeply hydrated, and entirely natural-looking results without added volume.
The Rejuran Healer – The Science of Salmon DNA
At the heart of Rejuran Skin Booster lies a breakthrough in regenerative aesthetic medicine: Polynucleotide (PDRN) therapy derived from ultra-pure salmon DNA. Unlike traditional hyaluronic acid treatments, which are designed to correct structure and volume loss, Rejuran injections improve skin quality by regenerating the skin on a cellular level.
Highly purified polynucleotides derived from salmon DNA are valued for their excellent biocompatibility and their ability to support the skin’s natural repair mechanisms. Once expertly injected into your skin’s deep dermis, these polynucleotides act as biological messengers. They stimulate natural collagen synthesis, repair micro-damage, and boost the skin’s own regenerative capacities, resulting in improved healing, renewed dermal structure, and enhanced elasticity and radiance.
Rather than merely masking superficial flaws or adding artificial volume, Rejuran activates a profound structural rejuvenation from within. By restoring your skin’s cellular foundation, this premium treatment delivers a multi-dimensional transformation across three key areas:
- Glass Skin Finish: Polynucleotide therapy helps refine the appearance of acne scars and enlarged pores while improving skin texture and supporting balanced sebum production. The result is a smoother, more luminous, and beautifully even complexion.
- Skin Firmness & Collagen Support: The Rejuran injections gently enhance facial contours, especially across the cheeks and jawline, creating a subtle “Korean lift” without adding volume or looking artificial. You get lifted, tightened skin elasticity that feels entirely your own.
- Under-Eye Skin Repair: The delicate periorbital area often betrays the first signs of ageing and fatigue. Rejuran is remarkably effective in restoring collagen production, smoothing fine lines, and improving the appearance of fine lines and tired-looking under-eye skin.
TREATMENT DESCRIPTION
Rejuran Healer is an advanced, non-surgical skin rejuvenation treatment formulated with purified salmon-derived polynucleotides (PN). Unlike traditional dermal fillers that primarily restore volume, Rejuran focuses on improving overall skin quality by supporting the skin’s natural repair processes, stimulating collagen production, enhancing elasticity, and restoring a smoother, more radiant complexion.
ANESTHESIA
Mild and well tolerated. To maximise comfort, a high-strength topical numbing cream is applied to the treatment area for approximately 15 minutes before the micro-injections. Most patients describe the procedure as small, manageable pinpricks.
TREATMENT DURATION
The injection procedure typically takes 15–30 minutes, depending on the treatment area (full face, neck, or delicate under-eye area). Please allow approximately 45–60 minutes in total, including the preparation time.
NUMBER OF SESSIONS PER TREATMENT
For optimal results, an initial course of three sessions spaced 4 weeks apart is recommended. Maintenance treatments every 12 months may be advised to help preserve and enhance results, depending on your skin condition, lifestyle, and aesthetic goals.
SIDE EFFECTS
Downtime is minimal. Temporary redness, mild swelling, and small raised bumps (papules) at the injection sites may occur after treatment. These typically resolve naturally within 24–48 hours.
RESULTS
Initial improvements in hydration and skin texture are often visible within 2–4 weeks as skin quality begins to improve. Continued improvements in texture, elasticity, radiance, and overall skin appearance develop progressively following the recommended treatment protocol. Results typically last 6–12 months, depending on individual factors.
Before & After the Treatment
Before Treatment
To minimise the risk of bruising, patients may be advised to avoid alcohol, blood-thinning medications, anti-inflammatory medication such as ibuprofen, and high-dose vitamin E supplements before treatment. Your doctor will provide personalised guidance based on your medical history.
Aftercare
Keep the treated area clean and avoid touching the skin for the first few hours after treatment. Avoid heavy makeup for 24 hours and refrain from saunas, steam rooms, swimming pools, and strenuous exercise for 48 hours. Daily broad-spectrum SPF application is recommended to protect your skin and maintain results.
The Treatment Contraindications
Rejuran is suitable for patients looking to address fine lines, enlarged pores, dullness, uneven skin texture, dehydration, or early signs of ageing. It is suitable for a wide range of skin types, including sensitive and mature skin.
Rejuran may not be suitable for individuals who:
- Have a known severe allergy to seafood or salmon-derived products
- Are pregnant or breastfeeding
- Have active skin infections, open wounds, or significant inflammation in the treatment area
- Have medical conditions requiring further assessment
A personalised consultation with your doctor will confirm whether Rejuran is appropriate for you.
Your Step-by-Step Treatment Journey
- Personalised Consultation & Digital Skin Analysis:
Your treatment begins with a comprehensive medical consultation and Digital Skin Analysis, allowing your practitioner to precisely assess your skin condition and customise every aspect of your treatment plan.
- Preparation for Comfort:
A high-strength topical numbing cream is applied to the treatment areas and left to take effect for approximately 15 minutes, ensuring the procedure remains highly comfortable.
- Precision Micro-Injections:
Using a refined micro-injection technique, tiny amounts of Rejuran are carefully delivered into the skin of the face, neck, or delicate under-eye area. The treatment is performed with meticulous attention to even distribution, supporting natural skin regeneration with minimal downtime.
Our Patients Share Their Positive Experiences
When you trust your skin and aesthetic goals to us, you are choosing Geneva’s experienced team of aesthetic medicine doctors dedicated to personalised care, advanced techniques, and refined, natural-looking results.
Every treatment journey begins with a comprehensive medical consultation. Our doctors carefully assess your facial features, skin condition, and individual goals to create a personalised treatment plan designed to enhance your natural beauty while respecting your unique identity.
Clinic Founder & International Expert in Non-Surgical Aesthetic Medicine View Dr. Madi’s Full Profile
Dr Nasser Madi is the founder and director of the Aesthetic Medicine Clinic in Geneva, with over 15 years of experience in non-surgical aesthetic medicine. With a medical background from the Geneva University Medical School, he is an international expert injector, trainer, and speaker specialising in facial harmonisation, dermal fillers, botulinum toxins, biostimulators, skin rejuvenation, and advanced aesthetic treatments. He serves as a Global Teoxane Key Opinion Leader.
Dedicated to his philosophy of “The Invisible Touch,” Dr Madi focuses on achieving balanced, sophisticated results that enhance facial harmony while preserving each patient’s natural expression.
As a master of full-face aesthetics, his signature treatment The Full Facial Rejuvenation Lift by Dr. Nasser significantly improves your face with the most natural, refreshed, and gratifying look.
Book your Consultation with Dr. Nasser!
Aesthetic Dental Surgeon & Aesthetic Medicine Specialist View Dr. Cerutti’s Full Profile
Dr. Diana Cerutti is an Aesthetic Dental Surgeon with specialised education and training in aesthetic medicine. She has completed advanced training with leading aesthetic institutions, mainly Teoxane but also other companies such as Galderma, Merz, and IBSA, and is certified by the European College of Aesthetic Medicine and Surgery (ECAMS). A faculty member of the Swiss Aesthetic Medicine & Business Academy (SAMBA) and Key Opinion Leader for Merz Aesthetics, Dr. Cerutti brings advanced expertise and a refined understanding of facial aesthetics to her practice. Guided by her “less is more” philosophy, she focuses on subtle, precise enhancements that preserve facial balance and reveal each patient’s natural beauty.
Book your Consultation with Dr. Cerutti!
Dr Denis Mailliu is a distinguished Aesthetic Medicine Physician certified in advanced oculoplastic aesthetics and surgical injection techniques.
A Key Opinion Leader and expert trainer for Teoxane, Dr Denis brings 25 years of clinical mastery to Geneva. Adopting a subtle, individualised approach, he specialises in facial contouring, collagen biostimulation, and regenerative therapies designed to elevate your authentic beauty.
Book your Consultation with Dr Denis!
How is Rejuran different from a traditional Korean facial or topical skincare?
Topical Korean skincare, no matter how luxurious, only works on the outermost layer of your skin (the epidermis). While facials deliver temporary hydration, they cannot reach the deep dermis where true cellular regeneration happens.
Polynucleotide therapy injects active salmon DNA directly into the dermal layer, precisely where skin quality, acne scars, and tissue elasticity are restored. If you have invested in top-tier serums but haven’t seen long-term structural improvements, Rejuran offers a completely new standard of skin recovery.
What is the difference between Rejuran and Botulinum Toxin?
A common question we hear is whether to choose Rejuran or Botox. The answer depends entirely on your aesthetic goals, as these injectables work in fundamentally different ways:
| Feature | Rejuran (PDRN) | Botox (Neurotoxin) |
| How it works | Stimulates natural collagen & repairs cells from within. | Temporarily relaxes facial muscles to block expression lines. |
| Best for | Skin quality, enlarged pores, acne scars, under-eye dark circles. | Forehead lines, crow’s feet, and frown lines. |
| Timeline | Results emerge in 2–4 weeks; lasts 6–12 months. | Results appear in 3–7 days; typically lasts 3–4 months. |
Can Rejuran be combined with other treatments?
Yes. Rejuran can be safely combined with selected aesthetic treatments to enhance overall skin rejuvenation. Depending on your skin concerns and treatment goals, it may be used alongside biostimulators such as Sculptra or Radiesse, or complementary procedures like microneedling and light therapy.
During your consultation, we will recommend a personalised treatment plan and advise on the safest and most effective combination for your skin.
When choosing a treatment, understanding the differences between leading collagen biostimulators helps ensure you make the right decision for your skin and lifestyle. Here is a clear comparison for our Geneva and international patients:
| Treatment | Onset of Results | Duration | Best Indication/Use | Ideal Patient Profile |
| Sculptra® (PLLA) | Gradual, noticeable from 12+ weeks | 18–24 months | Structural improvement, facial contour | Seeks slow, steady improvement, accustomed to advanced treatments |
| Radiesse® (CaHA) | Immediate volume, biostimulation over weeks | 12–18 months | Quick lifting, jawline, backs of hands | Prefers instant result with scaffold effect |
| Profhilo® | Immediate glow, peak at 4 weeks | 6–9 months | Deep hydration, fine lines, crepey skin | Younger patients, or as a foundation for combination therapies |
Why choose medical Rejuran treatment rather than a beauty clinic or facial?
Rejuran is an injectable medical treatment that requires precise technique, anatomical knowledge, and clinical assessment. At the Aesthetic Medicine Clinic, each treatment is performed by experienced aesthetic medicine doctors who personalise the approach according to your skin condition and aesthetic goals..






