Experience advanced PLLA collagen biostimulation with JULÄINE of Sweden for natural-looking skin rejuvenation at Aesthetic Medicine Clinic by Dr Nasser Madi in Geneva.
Harnessing unique poly-L-lactic acid (PLLA) technology, JULÄINE moves beyond traditional fillers to rebuild your skin’s architecture and restore firmness from within. Aligned with our philosophy of “The Invisible Touch,” this CE-marked treatment delivers subtle, enduring improvement and graceful ageing under expert medical guidance.
The Regenerative PLLA Science Behind JULÄINE
How Advanced Collagen Biostimulation Reinforces Your Skin
JULÄINE of Sweden is an advanced collagen biostimulator based on highly purified poly-L-lactic acid (PLLA) (a safe, medical-grade material that prompts natural skin renewal) microspheres suspended in a proprietary LASYNPRO matrix (a specialized technology ensuring smooth, even product distribution).
Unlike conventional hyaluronic acid fillers that primarily “fill” tissue, JULÄINE, initiates a cascade of biocellular responses: its microspheres interact with fibroblast cells, triggering a controlled, sustained synthesis (natural production) of new Type 1 collagen (the main protein responsible for skin firmness) and elastin (the protein that gives skin its stretch and bounce).
The LASYNPRO technology delivers uniform particle size and precise dispersion, activating your skin’s extracellular matrix via mechanical signalling rather than simply hydrating the tissue. This process gradually supports the skin’s renewal, visibly reversing structural changes due to ageing, sun exposure, or lifestyle stressors. Over several months, the biostimulation effect leads to firmer, more resilient skin, with restored elasticity and volume without overcorrection or artificial contours.
Swedish medical engineering underpins every vial: JULÄINE is ISO accredited and CE-marked, guaranteeing biocompatibility, purity, and safety for discerning patients across all skin tones, from very fair to deeply pigmented.
Rather than simply masking superficial flaws or adding temporary volume, JULÄINE awakens your skin’s innate regenerative capabilities from within. By rebuilding your dermal architecture, this advanced biostimulator delivers a multi-dimensional transformation across key areas of facial vitality:
- Facial Volume & Contour Restoration: Gracefully restores facial volume loss resulting from age or rapid weight reduction, including dedicated support for concerns like Ozempic face (hollow, sagging, and aged appearance of the face that can occur after rapid and significant weight loss from using semaglutide medications)
- Deep Wrinkle & Fold Smoothing: Smooths deep wrinkles and nasolabial folds by actively enhancing your skin’s underlying structural support.
- Definition & Natural Lift: Refines jawline and chin contours to provide improved definition and a subtle, natural lift.
- Laxity Reduction: Reduces visible skin laxity to reveal a firmer, beautifully uplifted appearance.
- Quality & Resilience: Boosts overall skin quality, including elasticity, consistency, and resilience against environmental stress.
TREATMENT DESCRIPTION
JULÄINE of Sweden is a next-generation, injectable collagen biostimulator that rebuilds and rejuvenates facial skin by activating your body’s own collagen synthesis for long-lasting firmness and refined facial contours.
Target Areas
- Mid-face (cheeks, cheekbones)
- Jawline and chin
- Lower face and oral expressions
- Temples (the flat areas on the sides of your face, located just outside your eyes and above your cheekbones)
- Deep folds (nasolabial, marionette lines)
- Other areas upon medical assessment
Comfort Level & Anaesthesia
Enhanced comfort protocols are standard. Prior injection, topical numbing cream is applied to minimise sensation. The advanced injection technique, coupled with fine cannulas chosen by your doctor, further reduces discomfort. JULÄINE’s formulation is engineered for smoother injection and reduced post-treatment irritation.
TREATMENT DURATION
The procedure typically takes 15-30 minutes, depending on the customised treatment plan and the number of facial zones addressed. Your total clinic time, including assessment and aftercare review, is approximately 45 minutes.
NUMBER OF SESSIONS PER TREATMENT
For optimal results, an initial protocol of 2-3 treatment sessions spaced 4- 6 weeks apart is recommended, based on your aesthetic goals and degree of laxity. Maintenance treatments are generally advised annually or as individually determined during follow-up.
SIDE EFFECTS
Certain mild side effects, such as redness, swelling, tenderness, or minor bruising, may occur at injection sites and usually resolve within 24-72 hours. Most patients resume daily activities immediately. Temporary firmness or palpable nodules can occasionally arise as collagen forms, but these are rare when administered by expert doctors.
RESULTS
Immediate improvement in hydration and slight volume may be visible after injection; however, the true rejuvenating effect emerges gradually as new collagen is synthesised.
Noticeable improvements develop over 8-12 weeks, continuing to refine for up to 6 months. Results typically endure 18-24 months, providing lasting skin firmness and facial harmony.
Before & After the Treatment
Before Treatment
- Avoid blood-thinning medications (e.g., aspirin, ibuprofen) and supplements (vitamin E, fish oil) for 3-5 days unless prescribed by your physician.
- Abstain from alcohol for 24 hours before the appointment.
- Arrive with cleansed, makeup-free skin.
- Inform your doctor of any recent illnesses, active skin issues, or planned dental procedures.
Aftercare
- Gently massage treated areas for 5 minutes, 5 times daily, for 5 days essential for even dispersion and optimal collagen activation.
- Avoid strenuous exercise, saunas, and significant sun exposure for 48 hours.
- Do not apply intense skincare actives or makeup for at least 12 hours post-procedure.
- Use broad-spectrum sun protection and maintain a gentle skincare routine as recommended by your doctor.
The Treatment Contraindications
Ideal candidates are adults seeking subtle facial rejuvenation and improved skin quality. JULÄINE of Sweden is not suitable for patients with severe allergies to its ingredients, active infections, autoimmune disorders, pregnancy, breastfeeding, or those with a history of abnormal scarring or keloid formation. Clinical consultation is essential to confirm suitability and ensure safety.
Your Step-by-Step Treatment Journey
- Personalised Consultation & Assessment:
Your journey begins with a detailed consultation with one of our aesthetic doctors, including a clinical analysis of facial structure, skin elasticity, and unique ageing patterns. Together, you discuss your goals and expectations, allowing your doctor to tailor your JULÄINE of Sweden treatment plan for harmonious, natural outcomes. - Preparation:
On your scheduled day, your skin is thoroughly cleansed, and a topical anaesthetic is applied for approximately 15 minutes. The doctor reviews your medical history, recent medications, and ensures no contraindications exist. - Treatment Procedure:
- The JULÄINE solution is meticulously prepared for optimal performance.
- Strategic mapping of injection points is performed, aiming for both immediate balance and long-term regeneration.
- Using microcannulas, JULÄINE is injected into targeted subdermal layers, activating your skin’s repair mechanisms.
- Gentle massage follows, supporting even product distribution and maximising biostimulation.
- Your comfort and results are monitored throughout.
- Post-Treatment Review & Guidance:
Before leaving the clinic, your doctor provides individualised aftercare instructions and ensures you understand the “5x5x5” massage protocol. Follow-up visits are arranged according to your customised schedule for progressive assessment and maintenance.
Our Patients Share Their Positive Experiences
When you trust your skin and aesthetic goals to us, you are choosing Geneva’s experienced team of aesthetic medicine doctors dedicated to personalised care, advanced techniques, and refined, natural-looking results.
Every treatment journey begins with a comprehensive medical consultation. Our doctors carefully assess your facial features, skin condition, and individual goals to create a personalised treatment plan designed to enhance your natural beauty while respecting your unique identity.
Clinic Founder & International Expert in Non-Surgical Aesthetic Medicine
Dr. Nasser Madi is the founder and director of the Aesthetic Medicine Clinic in Geneva, with over 15 years of experience in non-surgical aesthetic medicine. With a medical background from the Geneva University Medical School, he is an international expert injector, trainer, and speaker specialising in facial harmonisation, dermal fillers, botulinum toxins, biostimulators, skin rejuvenation, and advanced aesthetic treatments. He serves as a Global Teoxane Key Opinion Leader.
Dedicated to his philosophy of “The Invisible Touch,” Dr. Madi focuses on achieving balanced, sophisticated results that enhance facial harmony while preserving each patient’s natural expression.
As a master of full-face aesthetics, his signature treatment The Full Facial Rejuvenation Lift by Dr. Nasser, significantly improves your face with the most natural, refreshed, and gratifying look.
Book your Consultation with Dr. Nasser!
Dr. Diana Cerutti
Dr. Denis Mailliu
What distinguishes JULÄINE of Sweden from traditional hyaluronic acid fillers?
While hyaluronic acid fillers deliver immediate volume through hydration and gel lift, JULÄINE activates your body’s long-term collagen and elastin production for true, structural renewal. The outcome is gradual, subtle, and exceptionally natural.
How does JULÄINE compare to other biostimulators like Sculptra, Profhilo, or Radiesse?
When choosing the right aesthetic pathway, JULÄINE can be easily compared to other popular injectables depending on your specific goals. For instance, those seeking structural facial support often consider options like Sculptra, while patients prioritising deep hydration and fine-textured skin improvement frequently explore Profhilo. Additionally, individuals looking for immediate contouring or targeted volume can look into Radiesse or standard hyaluronic acid treatments to find the ideal match for their unique anatomy.
| Product | Onset of Results | Duration | Best Indication | Ideal Patient Profile |
| JULAÏNE of Sweden | Gradual, 8–12 weeks | 18–24 months | Collagen loss, laxity, sagging | Subtle rejuvenation seekers. Prevention |
| Sculptra™ | Gradual, 6–12 weeks | 18–24 months | Volume loss, skin laxity | Structural facial loss |
| Profhilo® | 2–3 weeks | 6–9 months | Hydration, crepey skin | Fine-textured skin improvement |
| HA Filler | Immediate | 12-18 months | Full face approach or localized indications such as temple and under-eye hollows, lips, jawline, nasolabial folds. | Instant effect desired |
Our aesthetic medicine doctors will guide you toward the best treatment option tailored specifically to your unique skin type during your consultation.
Can JULÄINE of Sweden be combined with other non-injectable treatments?
JULÄINE is compatible with many injectables procedures and can be safely integrated into bespoke rejuvenation programmes. Device-based treatments are assessed individually; your doctor will recommend the most appropriate protocol for your skin and goals.
JULÄINE can be safely integrated with advanced non-injectable options like Radiofrequency Skin Tightening, Laser Skin Resurfacing, or Medical Chemical Peels to refine surface quality. It also pairs seamlessly with complementary injectables such as Hyaluronic Acid Skin Boosters or Botulinum Toxin. Your aesthetic medicine doctor will recommend the best combination protocol tailored specifically to your unique skin type during your consultation.
What is the price for a JULÄINE treatment?
Pricing depends on the number of vials required, treatment areas, and the complexity of your bespoke plan. A transparent fee structure is discussed during your personal medical consultation. Please visit our Prices and Packages page to view detailed pricing for JULÄINE treatments in Geneva.





